Fig. 1

Construction of UCMSCs-Tandab(IL-6/CD20). A Schematic diagram of the Tandab recombinant vector (Tandab(CD20/IL-6)-6 × His-GFP vector). B Schematic representation to produce UCMSCs-Tandab(IL-6/CD20) and UCMSCs-Vector cell lines. With a lentivirus package, the Empty-GFP vector and Tandab(CD20/IL-6)-6 × His-GFP vector transfected HEK293T cells to collect empty and Tandab virus. Then, the empty and Tandab virus infected UCMSCs to produce UCMSCs-Vector and UCMSCs-Tandab(IL-6/CD20), respectively. C The morphology and fluorescence image of UCMSCs transfected with Tandab virus or empty virus under an inverted fluorescence microscope (Scale bar: 100 μm). Abbreviations: Tandab: Tandem diabody, GFP: Green fluorescent protein, 6 × His: Hexa-histidine tag