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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma

Fig. 2

Vitality, apoptosis and homing abilities of modified UCMSCs. A Cell viability of UCMSCs-Tandab(IL-6/CD20) and UCMSCs-Vector by CCK-8 assay. n = 5 for each group. B Apoptosis assay of UCMSCs-Tandab(IL-6/CD20), UCMSCs-Vector and UCMSCs by flow cytometry analysis. The histogram of apoptosis is shown in (C). (D) The migration ability of all three UCMSCs lines by transwell migration assay. Supernatants of SU-DHL-4 were used to trigger cells (UCMSCs-Tandab(IL-6/CD20), UCMSCs-Vector and UCMSCs) migration, and the CFM group served as a negative control. The numbers of migrated cells were statistically analyzed in (E). n = 3 for each group. ns: not significant, *p < 0.05, **p < 0.01. Abbreviations: CFM: Cell-free medium

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Stem Cell Research & Therapy

ISSN: 1757-6512