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Table 1 Patient characteristics

From: Unrelated umbilical cord blood can improve the prognosis of haploidentical hematopoietic stem cell transplantation

Parameter

UCB-haplo group (n, percent %)

Haplo group (n, percent %)

Age at HSCT, years

  

 < 20

15/53 (28.30%)

9/26 (34.62%)

 20–40

27/53 (50.94%)

11/26 (42.31%)

 > 40

11/53 (20.75%)

6/26 (23.08%)

Gender

  

 Male

27/53 (50.94%)

14/26 (53.85%)

 Female

26/53 (49.06%)

12/26 (46.15%)

Disease diagnosis

  

 AA

15/53 (28.30%)

4/26 (15.38%)

 MDS

11/53 (20.75%)

6/26 (23.08%)

 AML

15/53 (28.30%)

9/26 (34.62%)

 ALL

9/53 (16.98%)

5/26 (19.23%)

 Others

3/53 (5.66%)

2/26 (7.69%)

Disease status

  

 CR1

18/53 (33.96%)

7/26 (26.92%)

 CR2

2/53 (3.77%)

2/26 (7.69%)

 MRD positive

2/53 (3.77%)

1/26 (3.85%)

 PR

0/53 (0.00%)

5/26 (19.23%)

 NR

16/53 (30.19%)

7/26 (26.92%)

Donor recipient relationship

  

 Female-male

4/53 (7.55%)

4/26 (15.38%)

 Second-degree donor

4/53 (7.55%)

0/26 (0.00%)

 Others

45/53 (84.90%)

22/26 (84.62%)

Mismatched HLA

  

 3 loci

34/53 (64.15%)

13/26 (50.00%)

 2 loci

9/53 (16.98%)

5/26 (19.23%)

 0–1 locus

10/53 (18.87%)

8/26 (30.77%)

ABO match

  

 Matched

29/53 (54.72%)

13/26 (50.00%)

 Minor mismatched

10/53 (18.87%)

4/26 (15.38%)

 Major mismatched

10/53 (18.86%)

7/26 (26.92%)

 Major and minor mismatched

4/53 (7.55%)

2/26 (7.69%)

EBMT risk score

  

 0–1 point

17/53 (32.08%)

4/26 (15.38%)

 2–3 points

19/53 (35.85%)

9/26 (34.62%)

 4–6 points

17/53 (32.08%)

13/26 (50.00%)

  1. HSCT, hematopoietic stem cell transplantation; UCB-Haplo Group, haploidentical HSCT with an unrelated umbilical cord blood infusion; AA, aplastic anemia; MDS, myelodysplastic syndrome; AML, acute myeloid leukemia; ALL, acute lymphoid leukemia; CR, complete remission; MRD, minimal residual lesion; PR, partial remission; NR, non-remission; HLA, human leukocyte antigen; EBMT, the European group for blood and marrow transplantation