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Table 4 Multivariate analysis of the OS, PFS, TRM, and relapse rate in all patients

From: Unrelated umbilical cord blood can improve the prognosis of haploidentical hematopoietic stem cell transplantation

Variable

OS

PFS

TRM

Relapse

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Age

0.967 (0.444–2.105)

0.932

0.861 (0.429–1.729)

0.675

–

–

–

–

Disease status

1.187 (0.692–2.036)

0.533

1.281 (0.779–2.105)

0.329

1.090 (0.621–1.914)

0.764

1.254 (0.606–2.595)

0.542

EBMT risk score

1.804 (0.719–4.529)

0.209

1.876 (0.819–4.297)

0.137

1.560 (0.725–3.357)

0.256

2.816 (0.821–9.660)

0.100

cGVHD

0.199 (0.054–0.729)

0.015

0.232 (0.074–0.722)

0.012

0.228 (0.061–0.850)

0.028

–

–

Infection

2.964 (1.172–7.496)

0.022

2.165 (0.928–5.053)

0.074

4.104 (1.506–11.186)

0.006

–

–

UCB

0.331 (0.130–0.843)

0.020

0.338 (0.144–0.795)

0.013

0.329 (0.121–0.889)

0.028

0.243 (0.061–0.973)

0.046

  1. Bolded variable represented P < 0.05
  2. OS, overall survival; PFS, progression-free survival; TRM, transplant-related mortality; HR, hazard ratio; CI, confidence interval; EBMT, the European group for blood and marrow transplantation; GVHD, graft versus host disease. Factors with P > 0.05 were excluded