Fig. 7From: TNFα and IFNγ rapidly activate PI3K-AKT signaling to drive glycolysis that confers mesenchymal stem cells enhanced anti-inflammatory propertyA schematic model of anti-inflammatory effects of MSCs on IBD mice. PI3K-AKT signaling regulates glycolysis in MSCs. PI3K-AKT signaling was activated rapidly leading to the increase of glucose uptake and HKII enzyme activity. Enhanced glycolysis in MSCs results in a more robust production of anti-inflammatory factorsBack to article page