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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: ABCB5+ mesenchymal stromal cells therapy protects from hypoxia by restoring Ca2+ homeostasis in vitro and in vivo

Fig. 7

ABCB5+ cells therapy in ApoE−/− mice after DLFA leads to reduced weight loss. A The survival rate of ApoE−/− mice after DLFA and receiving ABCB5+ MSCs (ABCB5+ MSCs) or saline (control) treatment (n = 12 in each group). B Body weight of each of the animals was assessed directly prior to induction of DLFA and 7 days thereafter. C Tarlov Scale changes before and 7 days after induction of DLFA. D A representative MRI scan after the DLFA operation (scale bar: 5 mm). The right femoral artery (FA) was blocked (yellow arrow) as compared to the left FA (white arrow). Data were represented as mean ± SD, n = 12 in ABCB5+ MSCs group, n = 12 in controls group, ns, not significant, *p < 0.05, **p < 0.01, ***p < 0.001

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