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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: ABCB5+ mesenchymal stromal cells therapy protects from hypoxia by restoring Ca2+ homeostasis in vitro and in vivo

Fig. 9

In-vivo ABCB5+ MSCs restore ER Ca2+ using the SERCA2a-PLN axis. A, B Representative SERCA2a, PLN, pPLN, and β-actin expression in bilateral gastrocnemius muscle (GM) samples from the 3 mice from control (A) and ABCB5 + MSC treated groups (B). Full-length blots are presented in Additional file 5: Fig. S5. C–E Densitometric quantification of C SERCA2a expression (normalized to left side), D PLN expression (normalized to left side) and E pPLN/PLN (normalized to left side). Data were represented as mean ± SD, n = 10 control and n = 12 in ABCB5+ MSCs group, ns, not significant, *p < 0.05

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