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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Tumor stemness score to estimate epithelial-to-mesenchymal transition (EMT) and cancer stem cells (CSCs) characterization and to predict the prognosis and immunotherapy response in bladder urothelial carcinoma

Fig. 1

Overview of single-cell and prognostic value of each type cell’s biomarker in BLCA tissue. A The EMT process in tumor tissue. B The t-SNE plot of all the single cells, with each color coded for 4 major cell types. C Differentiation trajectory of epithelial cells in BLCA, with each color coded for cell types (top), pseudotime (medium), and statues (bottom). D Kaplan–Meier curves for high/low state 1 ssGSEA score groups in TCGA BLCA cohort. Log-rank test, p = 0.024. E Kaplan–Meier curves for high/low tissue stem cells ssGSEA score groups in TCGA BLCA cohort. Log-rank test, p = 0.007

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