Table 1 Association of the TS score with somatic variants
Gene symbol | High TS score (%) | Low TS score (%) | p value |
|---|---|---|---|
TP53 | 113 (54%) | 76 (39%) | 0.0028 |
TTN | 84 (40%) | 76 (39%) | 0.8393 |
KMT2D | 59 (28%) | 43 (22%) | 0.1697 |
MUC16 | 48 (23%) | 49 (25%) | 0.6421 |
ARID1A | 52 (25%) | 45 (23%) | 0.7270 |
KDM6A | 36 (17%) | 53 (27%) | 0.0167 |
PIK3CA | 42 (20%) | 41 (21%) | 0.9020 |
SYNE1 | 33 (16%) | 37 (19%) | 0.4313 |
RB1 | 38 (18%) | 21 (11%) | 0.0478 |
KMT2C | 29 (14%) | 29 (15%) | 0.7787 |
HMCN1 | 33 (16%) | 25 (13%) | 0.4780 |
FGFR3 | 8 (4%) | 47 (24%) |  < 0.0001 |
RYR2 | 23 (11%) | 33 (17%) | 0.1124 |
MACF1 | 27 (13%) | 27 (14%) | 0.8838 |
EP300 | 31 (15%) | 23 (12%) | 0.3842 |
FLG | 31 (15%) | 21 (11%) | 0.2376 |
FAT4 | 33 (16%) | 18 (9%) | 0.0520 |
STAG2 | 21 (10%) | 27 (14%) | 0.2820 |
ATM | 25 (12%) | 21 (11%) | 0.7554 |
OBSCN | 19 (9%) | 27 (14%) | 0.1586 |