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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin

Fig. 3

Effect of insulin and rosiglitazone on adipogenic differentiation and leptin secretion of AS. A Quantification of mRNA levels of Cebpb, Pparg, Plin1, Adipoq, and Lep relative to white adipose tissue (WAT) of adult mice (dotted line) in AS at 15 days of adipogenic differentiation with cocktail i20, i2.000, or InRo. Data are presented as mean ± standard deviation, N = 4 per group. Two-way ANOVA with Tukey's post-test. B Leptin concentration in conditioned medium (100 spheroids per group, 48 h) at day 15 of adipogenic differentiation. N = 3. One-way ANOVA (F (2, 6) = 7.539; p = 0.0231). * p < 0.05; ns: not significant

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Stem Cell Research & Therapy

ISSN: 1757-6512