Fig. 1
From: Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine
Effect of hydralazine (HYD) and valproic acid (VPA) on adult and neonatal fibroblast cell viability. Dose–time response curves were performed to evaluate the effect of HYD (panel A and B) and VPA (panel C and D) on adult and neonatal fibroblast cell viability. Two-way ANOVA with Dunnett multiple comparison tests was used for comparisons between control and other groups. The combined effect of 30 µM HYD and 1 mM VPA on cell viability of adult (panel E) and neonatal (panel F) fibroblasts during 96 h. The Mann–Whitney U test was used for comparisons between the control and HYD + VPA group. Values are expressed as mean ± standard error of the median from three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001