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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine

Fig. 6

Expression analysis of genes implicated in DNA methylation and chromatin remodeling complexes by the effect of hydralazine (HYD). Adult and neonatal fibroblasts were treated for 72 h with 30 µM HYD. Total RNA was extracted for each group and RT-qPCR assays were performed for DNMT1 (panel A), TET3 (panel B), ARID1 (panel C), and ARID2 (panel D) genes. Gene expression analysis were performed by technical triplicate of three biological replicates. Values are expressed as mean ± SEM. The Mann–Whitney U test was used for comparisons between groups. *P < 0.05

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