Fig. 9
From: Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer
Recovery of cellular respiration activity in ρ0 cells that received mtDNA from MSCs/RECs. Oxygen Consumption Rate (OCR) of A549 (A) and HeLa (B) cell lines from different groups was measured over time (minutes). The injection order of Oligomycin (Olig), FCCP, and antimycin A and Rotenone (AA/Rot) are shown. Basal mitochondrial OCR, ATP production, and maximum respiration of A549 (C) and HeLa (D) cell lines from different groups were calculated. E OCR of ρ0 A549 + REC and ρ0 HeLa + REC groups was measured over time (minutes). Basal mitochondrial OCR, ATP production, and maximum respiration of MSC and REC were calculated. F OCR of MSC and REC groups was measured over time (minutes). Basal mitochondrial OCR, ATP production, and maximum respiration of MSC and REC were calculated. All co-culture groups were in non-contact co-culture system. Data were based on three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001