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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Superior protective effects of PGE2 priming mesenchymal stem cells against LPS-induced acute lung injury (ALI) through macrophage immunomodulation

Fig. 7

Therapeutic mechanisms of PGE2-MSCs in LPS-ALI mice A-D Representative immunoblot and expression analysis of SMAD3, MMP2, and α-SMA in LPS-induced ALI mice. E qRT‒PCR analysis of IL-6 mRNA in LPS-ALI mice monitored for 24 h, 48 h, and 72 h. F qRT‒PCR analysis of IL-1β mRNA in LPS-ALI mice monitored for 24 h, 48 h, and 72 h. G qRT‒PCR analysis of TNF-α mRNA in LPS-ALI mice monitored for 24 h, 48 h, and 72 h. H qRT‒PCR analysis of IL-10 mRNA in LPS-ALI mice monitored for 24 h, 48 h, and 72 h. Data are represented as the mean ± SEM. *P < 0.05 vs ALI;#P < 0.05 vs PBS; &P < 0.05 vs MSC

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