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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis

Fig. 6

EpSCs enhanced the vascularization of dermal substitutes and novel tissue-engineered skin. A, B Representative area and analysis of wound tissue sections subjected to α-SMA staining on postinjury day 3 revealed microvascular regeneration in rat wounds in the ADM group and AE group. C, D Representative area and analysis of wound tissue sections subjected to α-SMA staining on postinjury day 7 in the ADM group and AE group. E Representative blood perfusion images of different skin graft groups at 1, 2, and 3 weeks after surgery. F Relative perfusion unit values at 1, 2, and 3 weeks (n = 3). G, H Representative area and analysis of wound tissue sections subjected to α-SMA staining at week 3 postinjury show microvascular regeneration in rat wounds of the ASE, AS, and STSG groups. A indicates acellular dermal matrix (ADM), N indicates normal skin, and S indicates STSG skin. The arrows indicate the microvasculature. Red scale bar: 1 mm, white scale bar: 50 μm

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