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Table 3 Evaluation of the efficacy of mesenchymal stem cells in the treatment of radiation-induced Xerostomia

From: Efficacy of mesenchymal stem cell therapy in rodent models of radiation-induced xerostomia and oral mucositis: a systematic review

Author/years

Salivary proteins

Salivary gland flow rate

Salivary lag time

Cytoprotection

Anti-apoptotic effects

Micromorphology

Macromorphology

An et al. 2015 [39]

+

+

+

+

+

+

+

Kim et al. 2019 [40]

+

+

+

+

+

+

+

Choi et al. 2018 [15]

+

+

+

+

+

+

+

Shin et al. 2018 [41]

+

+

+

+

–

+

+

Lim et al. 2013 [30]

+

+

+

–

+

+

+

Saylam et al. 2017 [43]

–

–

–

–

–

–

–

Lim et al. 2013 [42]

+

+

+

–

+

+

+

Mulyani et al. 2019 [44]

+

–

–

–

+

+

–

  1. Mention: +; Not Mention: –