Table 4 Evaluation of the efficacy of mesenchymal stem cells in the treatment of radiation-induced Oral mucositis
Author/years | Ulcer latency time | Duration of ulcers | Micromorphology | Macrosmorphology | The side effects of RIOM | BCL-2 | The tolerance of the oral mucosa | Pro-inflammatory cytokines |
|---|---|---|---|---|---|---|---|---|
Maria et al. 2016 [38] | + | + | + | + | + | – | – | – |
Elsaadany et al. 2017 [13] | – | – | + | – | – | + | – | – |
Schmidtet al. 2014 [14] | + | + | – | – | – | – | + | – |
Shen et al. 2018 [35] | – | – | + | + | – | – | – | + |