Table 5 SYRCLE’s RoB tool for each experimental animal study

Random Sequence Generation

Baseline Characteristics

Allocation Concealment

Random Housing

Blinding (study Team)

Random Outcome Assessment

Blinding (Outcome Assessors)

Incomplete Outcome Data

Selective Outcome Reporting

Other sources of bias

Selection bias

Performance bias

Detection bias

Attrition bias

Reporting bias

Other