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Fig. 11 | Stem Cell Research & Therapy

Fig. 11

From: The pluripotent factor OCT4A enhances the self-renewal of human dental pulp stem cells by targeting lncRNA FTX in an LPS-induced inflammatory microenvironment

Fig. 11

Effect of FTX on the expression of OCT4A and other pluripotent transcription factors in hDPSCs. A Expression of the OCT4A gene was upregulated after the interference of FTX expression in hDPSCs for 48 and 72 h. B Expression of the OCT4A gene showed a gradually declining trend in hDPSCs treated with an increasing MOI of FTX overexpression lentivirus. C–F Expression of OCT4A, SOX2 and c-MYC in FTX-knockdown or FTX-overexpressing hDPSCs. (C&D: mRNA expression; E1&F1: Representative bands of the protein expression; E2&F2: Quantitative analysis results of western blotting; Full-length blots are presented in Additional file 4; *: compared with the vector group, P < 0.05; **: compared with the vector group, P < 0.01; ***: compared with the vector group, P < 0.001; ∆: compared with the LPS stimulation group, P < 0.05; ∆∆: compared with the LPS stimulation group, P < 0.01; ∆∆∆: compared with the LPS stimulation group, P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512