Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: The pluripotent factor OCT4A enhances the self-renewal of human dental pulp stem cells by targeting lncRNA FTX in an LPS-induced inflammatory microenvironment

Fig. 2

Effect of OCT4A on the prolifeation of hDPSCs. A, B The CCK-8 assay showed that the inflammatory stimulus with 1 μg/mL LPS significantly inhibited the proliferation of hDPSCs. Overexpression of OCT4A alleviated the changes in cell proliferation caused by LPS stimulation, while knockdown of OCT4A further attenuated the proliferation of hDPSCs. C, D EdU staining showed that overexpression of OCT4A obviously increased the percentage of EdU-positive cells in LPS-treated hDPSCs, while EdU-positive cells were markedly inhibited by OCT4A interference. *: compared with the vector group, P < 0.05, **: compared with the vector group, P < 0.01; ∆: compared with the LPS stimulation group, P < 0.05; ∆∆: compared with the LPS stimulation group, P < 0.01

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512