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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway

Fig. 4

ApoVs treatment reduced noise-induced oxidative stress in OHCs. a Representative confocal microscopy images showing the immunofluorescence of 4-HNE in OHCs. Scale bar = 50 μm. Phalloidin staining (green) illustrating the outer hair cells structure. 4-HNE: 4-hydroxynonenal. b semi-quantification of fluorescence intensity of 4-HNE in OHCs. N = 6 per group. c representative confocal microscopy images showing the immunofluorescence of 3-NT in OHCs. Scale bar = 50 μm. Phalloidin staining (green) illustrating the OHCs structure. 3-NT: 3-nitrotyrosine. d semi-quantification of fluorescence intensity of 3-NT in OHCs. N = 5 per group. Data are presented as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512