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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Evaluation of safety and efficacy of autologous oral mucosa-derived epithelial cell sheet transplantation for prevention of anastomotic restenosis in congenital esophageal atresia and congenital esophageal stenosis

Fig. 2

Epithelial cell sheet transplantation into subject 2. A Endoscopic image of the stenosis just before EBD at cell sheet transplantation. B Contrast esophagography during EBD just before cell sheet transplantation. Arrows indicate the stenosis. The balloon was filled with contrast at 1 atm of internal pressure. C Enlarged image of the esophageal stenosis. The dotted line on the left is approximately 15.1 mm, and the right is 11.5 mm. D Endoscopic image after EBD just before cell sheet transplantation. Arrows indicate the location of the laceration caused by EBD. E The cell sheets were applied to the mucosa dehiscence above the laceration using the transplantation device. F Contrast esophagography before EBD at cell sheet transplantation. Arrows indicate anastomotic stenosis. G Contrast esophagography approximately one month (39 days) after cell sheet transplantation. Arrows indicate the stenosis. H Contrast esophagography approximately 5 months (154 days) after cell sheet transplantation. Arrows indicate the stenosis. I Endoscopic image of the stenosis approximately 5 months (154 days) after cell sheet transplantation. Arrows indicate the location of the laceration caused by EBD immediately before transplantation. J Endoscopic image of the stenosis approximately 12 months (348 days) after cell sheet transplantation. Arrows indicate the location of the laceration caused by EBD immediately before transplantation

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