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Table 2 Echocardiography results

From: Immunomodulatory amnion-derived mesenchymal stromal cells preserve muscle function in a mouse model of Duchenne muscular dystrophy

Variable

WT (n = 4)

Control mdx ( n = 6)

hAMSC-mdx-4 (n = 8)

P-value

WT versus control mdx

Control mdx versus hAMSC-mdx-4

IVSd (mm)

1.0 ± 0.1

1.1 ± 0.1

1.1 ± 0.2

NS

NS

LVPWd (mm)

1.2 ± 0.2

1.2 ± 0.1

1.2 ± 0.4

NS

NS

LVDd (mm)

3.5 ± 0.1

3.7 ± 0.2

3.6 ± 0.2

NS

NS

LVFS (%)

39.6 ± 3.9

33.6 ± 1.9

37.0 ± 2.3

0.008

0.017

  1. IVSd, interventricular septal thickness at end-diastole; LVPWd, left ventricular posterior wall thickness at end-diastole; LVDd, left ventricular diameter at end-diastolic; LVFS, left ventricular fractional shortening at end-diastole were calculated by M-mode echocardiography of WT (n = 4), control mdx (n = 6), and four-time hAMSC treated-mdx (hAMSC-mdx-4, n = 5). Data are presented as the mean ± SD; statistical differences are expressed relative to wild-type (WT) or control mdx mice; NS, not significant; t-test
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Stem Cell Research & Therapy

ISSN: 1757-6512