Fig. 1

Transplantation of Thy1-LSPCs and Thy1-MCs to Ret/PH-treated rat livers. A Schematic diagram showing the cell transplantation method. B Photos of SHPC clusters (black dotted lines) in hematoxylin–eosin (HE)-stained livers transplanted with control (left), Thy1-LSPCs (center), and Thy1-MCs (right). Inset depicts enlarged typical SHPCs (yellow square) in livers with and without Thy1⁺ cell transplantation. Fine fat droplets (empty vesicles) are observed in the cytoplasm of SHPCs. Scale bar, 500 μm. C The number of SHPC clusters per area and D area of the cluster were measured 14 days after transplantation. E Il17rb expression in SHPCs of livers that underwent Thy1⁺ cell transplantation was verified via qRT–PCR. Asterisks indicate significant differences at p < 0.05