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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

Fig. 2

SOCS3 upregulation in islet cells following pre-culture with SDF-1. SDF-1 treatment induces SOCS3 expression in vitro. A, B SOCS3 mRNA and protein levels were analyzed in islet cells following 48 h pre-culture with 0, 5, 10, 20 nM SDF-1. C Western blot analysis of SOCS3 levels in SOCS3 KO and Wt islets following 48 h pre-culture with or without 10 nM SDF-1. *p < 0.05 versus 0 nM SDF-1

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Stem Cell Research & Therapy

ISSN: 1757-6512