Fig. 6

SDF-1 abrogate T cell infiltration in transplanted SOCS3-KO islets. Kidney islet allografts were excised 40 days post-transplant, sectioned, and then stained with immunofluorescence to detect CD4 or CD8 T cells (red), insulin (green), or DAPI in SOCS3-KO islets with or without SDF-1 (A). Magnification: × 200. Three fields of vision were assessed for five mice from each group, and the numbers of infiltrating cells of the indicated subtypes were determined (B). *p < 0.05