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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

Fig. 7

In vivo administration of AMD3100 suppresses SDF-1-mediated immunosuppression in transplanted SOCS3-KO islets. A Graft mRNA was analyzed by qRT-PCR for inflammatory cytokines. B Protein concentrations in recipient mouse sera were determined by ELISA. C Flow cytometry analysis of the frequency of CD4+ FOXP3+ T cells. *p < 0.05

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