Fig. 7From: SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic miceIn vivo administration of AMD3100 suppresses SDF-1-mediated immunosuppression in transplanted SOCS3-KO islets. A Graft mRNA was analyzed by qRT-PCR for inflammatory cytokines. B Protein concentrations in recipient mouse sera were determined by ELISA. C Flow cytometry analysis of the frequency of CD4+ FOXP3+ T cells. *p < 0.05Back to article page