Skip to main content
Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats through autophagy-mediated anti-senescent mechanism

Fig. 10

Effects of MSC-CM on autophagic flow of rat podocytes induced by high glucose. A qPCR was performed to detect the expression of autophagy-related genes, including Beclin-1, p62, LC3B, and ULK1. B WB was performed to measure expression of autophagy-related proteins including Beclin-1, p62, LC3, and ULK1. C Expressions of autophagic pathway proteins, including AMPK, p-AMPK, mTOR and p-mTOR. Full-length blots of rat podocytes were presented (Additional file 2: Figs. S12–S16), respectively. Data were shown as mean ± SD, n = 3, unpaired, student’s t test. *P < 0.05 and **P < 0.01 versus the normal group, #P < 0.05 and ##P < 0.01 versus the model group

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512