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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats through autophagy-mediated anti-senescent mechanism

Fig. 5

Effects of hucMSCs on renal protein expressions in diabetic rats. A and B The representative images (200×) (scale bar = 50 μm) and the average optical density values of immunohistochemical staining of p-AMPK and p-mTOR. C Representative images of p-AMPK, p-mTOR, p16, and GADPH in renal tissues in WB analysis. Full-length blots of renal tissue were presented (Additional file 2: Figs. S26–S29 and Additional file 3: Fig. S34), respectively. D, E and F Relative protein expressions of p-AMPK, p-mTOR, and p16 to GADPH in WB analysis. Data were shown as mean ± SD, n = 3, unpaired, student's t test. *P < 0.05 and **P < 0.01 versus the normal group, #P < 0.05 and ##P < 0.01 versus the model group

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Stem Cell Research & Therapy

ISSN: 1757-6512