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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats through autophagy-mediated anti-senescent mechanism

Fig. 8

Molecular regulations of MSC-CM on high glucose-induced senescence of rat podocytes. A qPCR was performed to detect the expressions of senescence-related genes, including senescence markers p16, p21, p53, and pRb. B WB was performed to measure the expression of senescence-related proteins, including p16 and p53. Full-length blots of rat podocytes were presented (Additional file 2: Figs. S5–S7), respectively. Data were shown as mean ± SD, n = 3, unpaired, student’s t test. *P < 0.05 and **P < 0.01 versus the normal group, #P < 0.05 and ##P < 0.01 versus the model group

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Stem Cell Research & Therapy

ISSN: 1757-6512