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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling

Fig. 4

MT weakened ROS production and promoted osteogenesis in SONFH rats. A The ROS level of the femoral head was detected by DHE. B Representative immunohistochemical staining for OCN, Osterix and RUNX2 in decalcified bone sections. C Mean fluorescence intensity of ROS. D OCN-positive cells, E Osterix-positive cells and F RUNX2-positive cells. (*p < 0.05 and **p < 0.01 compared with the MP group. Scale bar: 100 μm.)

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Stem Cell Research & Therapy

ISSN: 1757-6512