Fig. 2

AT-hMSCs better protected target organs of aGvHD. A Representative photographs of H&E-stained liver, colon and spleen tissues on day 21. Scale bar = 100 μm. White arrows = apoptotic bodies, black arrows = crypt loss, arrowhead = atrophy of surface epithelium, * = loss of white pulp. B, D CCL3 and C, E CXCL9 mRNA expression in mouse liver B, C and colon D, E on days 7 and day 21 post-transplantation. Graphs show data from three experiments with mean + / − SEM. Significance was calculated relative to positive control group (TCDBM + CD4) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001