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Table 2 Number of MDS patients and patient characteristics of the material used for xenotransplantation

From: Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free medium

Patient characteristics

MSCs expanded with FBS

MSCs expanded with XF

Age

52–83

49–86

IPSS

low

1

4

int-1

6

5

int-2

4

4

high

0

1

WHO 2016

MDS-MLD

2

3

MDS-RS-MLD

1

1

MDS-EB1

2

3

MDS-EB2

4

3

tMDS

1

2

MDS-U

 

1

MDS with isolated del(5q)

1

1

  1. The table displays the number of patients used for xenografting and their patient characteristics like age, IPSS and WHO 2016 classification. Engraftment data generated in experiments using FBS cultured MSCs versus XF cultured MSCs were compared. To this end, we were able to compare engraftment data from n = 11 MDS patients transplanted with FBS cultured MSCs with n = 14 MDS patient samples transplanted with XF medium
  2. MDS Myelodysplastic Neoplasms, IPSS MDS risk score according to international prognostic scoring system, FBS Fetal bovine serum, int Intermediate