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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: TRPA1 promotes the maturation of embryonic stem cell-derived cardiomyocytes by regulating mitochondrial biogenesis and dynamics

Fig. 1

TRPA1 improved the structural maturation of mESC-CMs. A Representative confocal fluorescence images showing the staining of α-actinin. Scale bar = 25 μm. B, C Percentage of cells with disorganized sarcomeres for KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. Data were from 6 independent batches of differentiation. D, E Cell size for KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. n = 25–52 cells from 3 independent batches of differentiation. F–G Percentage of multi-nucleated cells in KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. Data were from 4 to 5 independent batches of differentiation. Data were presented as mean ± SEM. **P < 0.01; ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512