Fig. 3

TRPA1 improved the metabolic maturation of mESC-CMs. A, B Representative real-time respiration measurements of mESC-CMs and their responses to the subsequent injection of oligomycin (oligo), carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), and antimycin and rotenone (A/R). C, D Bar graphs showing the basal respiration, maximal respiration, ATP-linked respiration, and spare capacity in KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. Data from KD and OE groups were normalized to that of their respective control groups. Data were from three independent batches of differentiation. Data were presented as mean ± SEM. *P < 0.05; **P < 0.01