Fig. 4

TRPA1 improved the biogenesis and fusion of mitochondria in mESC-CMs. A Confocal microscopy images of mitochondria in KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. Scale bar = 25 μm. B, C Bar graphs showing the mitochondrial size (average mitochondrial area and branch length), mitochondrial complexity (number of branches and junctions per mitochondrion), mitochondrial number, and fractional occupancy. n = 15–39 cells from 3 independent batches of differentiation. Data were presented as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001