Fig. 5
TRPA1 improved the expression of genes related to the function and maturation of mitochondria and CMs. A, B Levels of mRNA transcripts encoding TRPA1, cardiac marker genes, ion channel genes, Ca2+ handling genes, t-tubule formation-related genes, mitochondrial biogenesis/dynamic-related genes, and fatty acid β-oxidation (FAO)-related genes in TRPA1 KD cells (A) and TRPA1 OE cells (B). The broken lines represented the relative expression level of genes in the control groups. KD control and TRPA1 KD cells were analyzed at day (7 + 9). OE control and TRPA1 OE cells were analyzed at day (7 + 7). Data were from 4 to 5 independent batches of differentiation. Results were expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001