Fig. 2
Changes in wounds after SVF-gel grafting. a Patient 8 was a 64-year-old male with postoperation varicose veins, hypertension, obesity, and femoral head necrosis and had an intractable chronic wound on the top of the medial malleolus. Preoperative view, after surgical debridement, original wound size was 14.60 cm2 (left 1). Transplantation of SVF-gel (left 2). Two weeks after the treatment of SVF-gel, the wound was mostly epithelialized. The remaining wound size was 3.06 cm2 (right 1). At 22 days after treatment, reepithelization of wound was completed (right 2). Three years post-surgery, the original necrosis area healed and no ulcers recurred (right 3). Scale Bar = 0.5 cm. b Patient 4 was a 73-year-old male with diabetes mellitus and had an intractable chronic wound on the top of lateral malleolus. Preoperative view (left 1). After surgical debridement, original wound size was 19.14  cm2 (left 2). Two weeks after the treatment of SVF-gel, the wound was partly epithelialized. The remaining wound size was 12.59 cm2 (left 3). Three weeks after treatment, the remaining wound size was 5.05 cm2 (right 1). Four weeks after treatment, the wound was mostly epithelialized. The remaining wound size was 2.54 cm2 (right 2). Six years post-surgery, the original necrosis area healed and no ulcers recurred (right 3). Scale Bar = 0.5 cm. c Patient 5 was a 74-year-old female with a chronic ulcer located above right medial malleolus for 5 months and had a history of great saphenous varicose vein. After surgical debridement, original wound size was 7.61 cm2 (left). Two weeks after treatment, the wound was mostly epithelialized. The remaining wound size was only 1.72 cm2 (middle). Three years post-surgery, the original necrosis area healed and no ulcers recurred (right). Scale Bar = 2 cm