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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Bioactivity of human adult stem cells and functional relevance of stem cell-derived extracellular matrix in chondrogenesis

Fig. 5

Schematic of the study. Schematic of the study. In this study, we characterized the bioactivity, particularly the chondrogenic induction ability, of the ECM produced by adult stem/progenitor cells derived from human adipose, bone marrow, and articular cartilage tissue. Our results suggest the presence of different in vivo cartilage regenerative potencies and patterns of adult stem cells derived from adipose, bone marrow, and cartilage tissue. FN: fibronectin; COL1, collagen type I; COL3, collagen type III; SOX9, SRY-box transcription factor 9; COL2A1, pro-alpha1(II) chain of type II collagen; AGN, aggrecan; CD44, cell surface glycoprotein, receptor of hyaluronic acid; ECM; extracellular matrix. Figure 5 was created with BioRender.com by the authors with license obtained

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Stem Cell Research & Therapy

ISSN: 1757-6512