The activation of dormant ependymal cells following spinal cord injury

Table 1 Changes of mRNA and protein expression in ependymal cells from injured spinal cord and grown as neurospheres in vitro

Gene symbol	Species	Expression	Reference(s)
P2Y1	Rat	↓ mRNA and prot	[79]
P2Y4	Rat	↑ mRNA and prot	[79]
Cx37	Rat	↓ mRNA and prot	[98]
Cx40	Rat	↓ mRNA and prot	[98]
Cx43	Rat	↓ mRNA and prot	[98]
Cx50	Rat	↓ mRNA and prot	[92, 98]
NCAM	Rat	↑ mRNA	[2]

Gene symbol	Species	Expression/time	Reference (s)
Changes of protein expression ependymal cells in injured spinal cord (central canal) in vivo
BAF45D	Rat	↓ prot/10–14 dpi	[59]
ATF3	Rat	↑ nuclear prot/6–24 h	[60]
Sox9	Mouse	↑ prot/2 w–10 mo	[13]
Β-Integrin	Mouse	↑ prot/2 dpi	[71]
GPR17	Mouse	↑ prot/72 h–1 w	[77]
Cx26	Mouse	↑ prot/5 dpi	[99]
Cx50	Mouse	↓ prot/1 w	[98]
OSMR	Mouse	↑ mRNA and prot/72 h	[61]
FoxJ1	Mouse	↓ prot/72 h	[61]
CXCR4	Mouse	↓ prot/5 w	[74]
NCAM	Rat	↑ prot/1–3 dpi	[72]

Gene symbol	Species	Expression/time	Reference (s)
Changes of protein expression in injured spinal cord in vivo within the region of hosted ependymal cells after transplantation
P2X4	Rat	↓ prot/2 mo	[79]
P2X7	Rat	↓ prot/2 mo	[79]
Cx50	Rat	↓ prot/2 mo	[92]

Messenger ribonucleic acid, (mRNA); protein, (prot). Days post-injury, dpi; hours, h; week, w; and month, mo

ISSN: 1757-6512