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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues

Fig. 4

Relative gene expression of A SOX2 B OCT4 and C) NANOG by iPS in FBS/PL. Expression is presented relative to the DF-iPS-FBS group ± SD. D Heatmap analysis of the gene expression of SOX2, OCT4 and NANOG by the fibroblasts in FBS/PL and their resultant iPS. Expression presented relative to the DF-FBS group. Independent samples t-test and one-way ANOVA were used to determine statistical significance (p < 0.05). (*) represents significance between iPS, from the same source, grown in FBS to those grown in PL. (+) represents significance between the iPS-FBS. (#) represents significance between the iPS-PL (DF: dermal fibroblasts, BF: buccal fibroblasts, GF: gingival fibroblasts, iPS: induced pluripotent stem cells, FBS: fetal bovine serum, PL: platelet lysate)

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Stem Cell Research & Therapy

ISSN: 1757-6512