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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: LncRNA00638 promotes the osteogenic differentiation of periodontal mesenchymal stem cells from periodontitis patients under static mechanical strain

Fig. 2

Microarray screening and analysis. A Hierarchical clustering and heatmap analysis were used to detect differentially expressed lncRNAs after 12% SMS loading. T1, T2, and T3 are control group samples taken from PPDLSCs without SMS loading, and PP1, PP2, and PP3 are experimental group samples taken from PPDLSCs with SMS loading. There were visible differences between the two groups. B Scatter plot showing variations in the expression of lncRNAs. Black dots are lncRNAs with a differential expression ratio < 2.0, red and green dots are lncRNAs with a differential expression ratio > 2.0. C Volcano plot showing the relationship between the fold changes in the expression of differentially expressed lncRNAs among sample groups and the corresponding statistical significance. Black dots indicate P > 0.05 and red and green dots indicate P < 0.05. D KEGG pathways enriched in mRNAs with increased expression (left) and decreased expression (right). E Top 10 BPs enriched in mRNAs with increased expression. F Top 10 BPs enriched in mRNAs with decreased expression. G Top 10 CCs enriched in mRNAs with increased expression. H Top 10 CCs enriched in mRNAs with decreased expression. I Top 10 MFs enriched in mRNAs with increased expression. J Top 10 MFs enriched in mRNAs with decreased expression

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Stem Cell Research & Therapy

ISSN: 1757-6512