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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: LncRNA00638 promotes the osteogenic differentiation of periodontal mesenchymal stem cells from periodontitis patients under static mechanical strain

Fig. 5

Mechanism by which lncRNA00638 regulates osteogenesis. A CNC network mapping for related mRNAs of differentially expressed lncRNAs. B CeRNA lncRNA00638 interaction network diagram. Green circle: lncRNA00638; red circle: miR-424-5p; pink circle: FGFR1. C Transfection efficiency of anti-miR-424-5p. D The expression of miR-424-5p after lncRNA00638-RNAi transfection. E The expression of lncRNA00638 after anti-miR-424-5p transfection. F Anti-miR-424-5p can promoted FGFR1 expression at the gene and protein levels (Full-length blots are presented in Additional file 2: Fig. S1). G FGFR1 gene and protein expression after the overexpression of LncRNA00638 (Full-length blots are presented in Additional file 3: Fig. S2). H FGFR1 gene and protein expression after the silencing of lncRNA00638 (Full-length blots are presented in Additional file 4: Fig. S3)

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Stem Cell Research & Therapy

ISSN: 1757-6512