Fig. 1

CSF total-tau and phosphorylated-tau levels. CSF (A) T-tau and (B) P-tau levels at baseline and one day after the third MSC injection in each group. Intergroup comparison of rate of changes in CSF (C) T-tau and (D) P-tau levels. In the Mixed effects model, we included time, group, baseline T-tau or P-tau levels, and time*group as fixed effect and subjects as random effects. *p < 0.05, **p < 0.001. GR Good Responder; PR Poor Responder; CSF Cerebrospinal Fluid; T-tau Total-tau; P-tau Phosphorylated-tau