Fig. 4
From: PAI-1 regulates AT2-mediated re-alveolarization and ion permeability
Effect of elevated PAI-1 on the bioelectric features of primary AT2 cells. a Schematic representation of AT2 cells monolayer cultures. b Transepithelial resistance (RT) of AT2 monolayers was measured with a chopstick meter (N = 16 monolayers per group). c Representatives short-circuit current (Isc) traces in response to accumulating amiloride doses. d Raw data from c were fitted with the Hill equation to compute the IC50 value. N = 12. Data are mean ± SEM and analyzed with one-way ANOVA followed by the Tukey post hoc test. *p ≤ 0.05 and **p ≤ 0.01 compared with wt controls