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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: PPARγ-dependent hepatic macrophage switching acts as a central hub for hUCMSC-mediated alleviation of decompensated liver cirrhosis in rats

Fig. 2

Effects of different hUCMSCs infusion regimens on the immune microenvironment in rat liver. A Flow cytometry analysis of the changing proportion of macrophages and their subtypes in liver tissues. B Percentage of macrophages and their subtypes in CD45 + T cells (n = 5). C The mRNA expression levels of M1 macrophage-related genes in the liver tissue (n = 5). D The mRNA expression levels of M2 macrophage-related genes in the liver tissue (n = 5). E The serum levels of inflammatory factors in rats based on the inflammation antibody array (NC and DLC group, n = 3; hUCMSCs group, n = 4). F Effect of hUCMSCs transplantation on the immune-related factors in liver tissues (n = 5). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, and ns (no statistical significance) (all p values were obtained by the two-tailed Student’s test)

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Stem Cell Research & Therapy

ISSN: 1757-6512