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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: PPARγ-dependent hepatic macrophage switching acts as a central hub for hUCMSC-mediated alleviation of decompensated liver cirrhosis in rats

Fig. 3

Upregulation of PPARγ in hUCMSC-treated DLC liver. A Venn analysis of the differential genes among the NC, DLC, and hUCMSCs groups. B KEGG pathways enrichment analysis of the selected differentially expressed genes. C Heat map of the immune-related genes among the differentially expressed genes. D To ascertain the results from RNA-seq, the mRNA levels of PPARγ expression were evaluated by qRT-PCR analysis (n = 5). E Protein levels of PPARγ in liver tissue (n = 4) (Full-length blots and repeated experiments are presented in Additional file 2). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, and ns (no statistical significance) (all p values were obtained by the two-tailed Student’s test)

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