Fig. 1

Assessment of muscle mass after ADSCs treatment in Dex-induced muscle atrophy mice. A Whole-body, hindlimb and forelimb composition including lean mass and fat mass measured by DXA machine. B Quantification of tibialis anterior (TA), gastrocnemius (GA), quadriceps femoris muscle (QA) extensor digitorum longus (EDL) and soleus muscle wet weight. C Quantification of muscle CSA in H&E stained GA muscle. D Analysis of muscle atrophy-related genes (Mstn, Atrogin-1 and Murf-1) and protein synthesis-related genes (p70s6k and e-IF4g-1) genes expression in TA muscles with ADSCs treatment. n = 6 per group. Quantitative data are presented as mean ± SD. Statistical analysis are performed using one-way ANOVA test, with significance set at P < 0.05 (*P < 0.05, **P < 0.01, ***P < 0.005, #P < 0.001)