Fig. 6

The effect of ERK1/2 inhibition on muscle quality in ADSCs-treated muscle atrophy mice. A Quantification of muscle wet weight of TA, EDL, GA, Soleus and QA muscle wet weight. B Hindlimb grip strength and normalised by whole body weight grip strength. C Ex vivo GA muscle tetanic and twitch fore with or without normalised by GA muscle CSA. D GA muscle fatigability and recovery rate measured by the contraction force of GA muscle after 5 min and 10 min of fatigue. E Immunofluorescence staining and quantification of fibre types in GA muscle. F Distribution of CSA of GA fibre. n = 6 per group. Statistical analysis are performed using t-test, with significance set at P < 0.05 (*P < 0.05, **P < 0.01, ***P < 0.005, #P < 0.001)