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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages

Fig. 4

Effects of hUC-MSC transplantation on spleen T cells and B cells in 14-week-old MRL/lpr mice. A Representative images of total T cells (a) and total B cells (b) in the spleens of each group of mice. Blue fluorescence represents DAPI, red fluorescence represents CD3 or CD19, and the scale bar is 100 μm. B Representative images of B cell subsets in the spleens of mice from each group, including Breg cells (a), plasmablasts (PB), and plasma cells (PC) (b). The images in the upper right corner are magnified five times. Blue fluorescence represents DAPI, red fluorescence represents CD19, and green fluorescence represents IL-10 or CD138, with a scale bar of 50 μm. The number of mice is n = 5

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